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O-Desmethyltramadol (O-DSMT) is an opioid that has primarily been used indirectly due to it being a primary metabolite of the analgesic tramadol. Since the 2010s it has occasionally been used on its own as it has been sold through the grey market/research chemical market. It has a longer duration than tramadol and more typical opioid-like effects, although it still impacts monoaminergic systems to an extent that might somewhat influence the effect profile. Buy o–DSMT? Buy Tramadol / muscle relaxant? The best quality for a fair price. Online Research Chemicals; shipped quickly, discreetly & securely. ............................................................buy guns online USA................
O-DSMT For Sale Online Dosage
Light: 15 – 30 mg
Common: 30 – 50 mg
Strong: 50 – 70+ mg
Some people report using doses in the hundreds of milligrams, including via more intense routes of administration like intravenous. Because too little information exists about higher doses and non-oral routes, it is best to stick with common oral doses.
It does seem true that some users fail to receive any notable effects at common doses and have to use over 100 mg to receive a positive experience. Despite this, common doses are still recommended as they will usually be sufficient in someone without a tolerance.
A few reports of rectal administration exist. When using via this route nausea might be reduced and it may be somewhat more potent vs. oral use, so dosing needs to be adjusted accordingly. Oral use is usually preferred to intranasal.
Effects Of O-DSMT Research Chemical
O-DSMT has not been studied for medical uses, but it likely has efficacy in the same conditions as typical opioids like oxycodone and morphine. Also, based on research with tramadol, there’s some evidence indicating how much benefit people receive from tramadol is at least partly dependent on how much O-DSMT they produce (Kirchheiner, 2008 ; Stamer, 2007 ; Poulsen, 1996).
An animal study in rats did find O-DSMT had analgesic effects and those were blocked by a MOR antagonist (Valle, 2000). The effects were seen with the (R) enantiomer, as the (S) enantiomer produced no antinociception or respiratory depression at 2 to 10 mg/kg IV
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